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Treatment of Generalized Hyperhidrosis

 

Benzodiazepines:

Benzodiazepines such as diazepam, a tranquilizer used to relieve anxiety and relax muscles may have an ameliorating effect for patients whose hyperhidrosis is related to specific anxiety producing events such as appearing in an interview.

Anticholinergics medications:

Ditropan (Oxybutynin) is useful in the relatively rare syndrome of episodic hyperhidrosis with hypothermia. Ditropan is an extended release medication taken once daily. Another anticholinergic, benztropine (Cogentin), is useful for treating venlafaxine-induced hyperhidrosis.

However, the dosages can also cause side effects such as mydriasis, cycloplegia, and bladder dysfunction, and most patients with hyperhidrosis cannot tolerate them for long. Robinul (Glycopyrolate)‚ is most effective in patients who have an emotional trigger to sweating during stressful situations such as public speaking.

Clonidine:

It is found to be useful in treating hyperhidrosis due to tricyclic antidepressants and menopause.